Meelad M. Dawlaty, PhD

Principal Investigator

Associate Professor, Department of Genetics

Associate Professor, Department of Developmental & Molecular Biology
Member, Institute for Stem Cell and Regenerative Medicine Research

Education:

  • B.A. Biology and Chemistry Concordia College, Moorhead MN, USA 2000-2003

  • Ph.D. Biomedical Sciences Cancer Biology, Mayo Clinic College of Medicine, Rochester, MN, USA               (Advisor: Prof. Jan van Deursen, PhD) 2004-2008

  • Postdoctoral Training: Epigenetics of stem cells & development, Whitehead Institute/MIT Cambridge, MA, USA (Mentor: Prof. Rudolf Jaenisch, MD) 2009-2014

Teaching:  

  • Molecular Genetics (Fall), Gene Expression (Winter), Stem Cells Development & Disease (Spring)

-------------------------------- Support Staff ------------------------------

Joun Lee, B.A.

Study Coordinator

Education:

  • B.A. Psychology, Emory University, Atlanta, Georgia, USA

About Joun: 

Joun joined the lab in September 2017 after completing his Bachelors degree at Emory University and working as a research assistant at Boston Children’s Hospital where he studied the biology of motor neurons in mouse models of ALS. He coordinates several mouse developmental and cancer studies and provides support in overseeing the generation and monitoring of animals in study. 

Nick Cheng-Yen Huang, B.A.

Technician/Lab Manager

Education:

  • B.A. Neuroscience, Boston University, Boston, MA, USA

About Nick: 

Nick joined the lab in July 2020 after completing his Bachelors degree at Boston University and finishing an internship at McLean Hospital in Boston where he worked with rat models of addiction. He oversees the daily lab maintenance as well as mouse colony genotyping and management. 

-------------------------------- Postdoctoral Fellows ------------------------------

Stephanie Chrysanthou, PhD

Postdoctoral Fellow

Education:

  • B.Sc. Biochemistry and Molecular Biology, University of Bristol, UK

  • M.Res. Biomedical Research, Imperial College London, UK

  • Ph.D. Epigenetics, Babraham Institute, University of Cambridge, UK

About Stephanie:

Stephanie joined the lab in August 2017 after completing her PhD in Epigenetics in Dr. Myriam Hemberger’s lab at the Babraham Institute in UK where she studied the role of Tet enzymes in regulation of trophoblast stem cell biology.  She is interested in dissecting the molecular functions of Tet enzymes in regulating gene expression programs in ESCs and their implications in stem cell self renewal and pluripotency.

Liyang Ma, PhD

Postdoctoral Fellow

Education:

  • B.Sc. Biotechnology, Shandong Agricultural University, China

  • M.Sc. Developmental Biology, The Institute of Zoology, Chinese Academy of Sciences, Beijing, China

  • Ph.D. Developmental Biology, The Institute of Zoology, Chinese Academy of Sciences, Beijing, China

About Liyang:

Liyang joined the lab in December 2017 after completing his PhD in Developmental Biology in Dr. Yanling Wang’s lab at the Institute of Zoology Chinese Academy of Sciences in Beijing China where he studied the interaction of the immune system and placenta, and its role in early pregnancy maintenance.  He is interested in defining the molecular and biological functions of Tet enzymes during lineage specification and in embryonic development.

Qin Tang, PhD

Postdoctoral Fellow

Education:

  • B.Sc. Biology, College of Life Sciences, Hubei University, China

  • M.Sc. Fishery Resources, College of Fisheries, Huazhong Agricultural University, China

  • Ph.D. Genetics & Bioinformatics, Institute of Hydrobiology, Chinese Academy of Sciences, China

  • Postdoc Fellowship, Computational & Systems Biology, Huazhong University of Science & Technology, China

About Qin:

Qin joined the lab in June 2018 after completing a postdoctoral fellowship in Dr. Guo's lab at Huazhong University where she studied the role of transcription factors and microRNAs in gene regulation in cancer. She is interested in investigating Tet-mediated epigenetic regulation of ES cells and cancer using a systems biology approaches.

Antoine Abou Jaoude, PhD

Postdoctoral Fellow

Education:

  • B.Sc. Biochemistry, Lebanese University, Fanar, Lebanon

  • M.Sc. Molecular Biology, Lebanese University, Hadath, Lebanon

  • Ph.D. Biology, University of Strasbourg, Strasbourg, France

About Antoine:

Antoine joined the lab in July 2019 after completing his PhD in Dr. Philippe Boucher laboratory at the University of Strasbourg where he studied signaling pathways involved in atherosclerosis and chondrogenesis using cellular and transgenic mouse models. He is interested in investigating how Tet enzymes are regulated in ESCs and how these mechanisms contribute to ESC pluripotency, development and cancer.

----------------------------------- Clinical Fellow --------------------------------

Kaitlin Haines, MD

Fellow in the Montefiore Fellowship Program in Gynecologic Oncology

Education:

  • M.D. Tufts University School of Medicine, Boston, MA, USA

  • Residency. Yale New Haven Hospital, CT, USA

About Kaitlin:

Kaitlin is a Fellow in the Montefiore Fellowship Program in Gynecologic Oncology. She joined the lab in July 2020 to conduct the one year research phase of her fellowship. She is interested in understanding the epigenetic regulation of endometrial cancers with an emphasis on how DNA methylation and hydroxymethylation dynamics influence tumorigenesis.

-------------------------------- Graduate Students ------------------------------

Julio Flores, BSc

M.D.Ph.D. Graduate Student

Education:

  • B.Sc. Molecular and Cellular Biology, University of California Merced School of Natural Sciences, CA, USA

  • M.D. & Ph.D. Dual Degree In Progress, Albert Einstein College of Medicine, Bronx, New York, USA

About Julio:

Julio joined the lab for his Ph.D. thesis work in August 2019. He has been part of MARC-U*START and UPSTaRT programs and the recipient of several awards as an undergraduate student. He worked as a research specialist at UCSF before joining Einstein M.D.Ph.D. Program in 2017. He is interested in investigating how the enzymatic and non-enzymatic functions of Tet enzymes regulate stem cell identity and plasticity, and their implications in development and cancer.

Harmony Ketchum, BSc

Ph.D. Graduate Student

Education:

  • B.Sc. Allied Health Science and Biology, Grand Valley State University, Michigan, USA

  • Ph.D. Degree In Progress, Albert Einstein College of Medicine, Bronx, New York, USA

About Harmony:

Harmony joined the lab for her Ph.D. thesis work in March 2020. She comes a with Bachelor degree in Health Science & Biology followed by two years of research experience as a technologist at Einstein where she studied the role of Colony Stimulating Factor 1 Receptor (CSF-R) in macrophage and microglia biology using mouse models. She is interested in understanding how DNA methylation and demethylation dynamics are regulated by Tet enzymes during stem cell differentiation and embryogenesis.  

Ian MacArthur, BA

M.D.Ph.D. Graduate Student

Education:

  • B.A. Biology Columbia University, New York, NY, USA 

  • M.D. & Ph.D. Dual Degree In Progress, Albert Einstein College of Medicine, Bronx, New York, USA

About Ian:

Ian joined the lab for his Ph.D. thesis work in August 2020. He has worked as a technologist at the Molecular Pharmacology Program in the Memorial Sloan Kettering Cancer Center and as a research associate at Department of Pediatric Oncology and Hematology at Charite-Universitatsmedizin in Berlin Germany before joining the Einstein M.D. Ph.D. program in 2018. He is interested in studying how Tet enzymes and the DNA base 5hmC regulate neural development and human developmental disorders.

Rotation Students:

MD/PhD students:

Blake Ebert, (Summer 2020)

Alexandra Schurer, (Summer 2020)

Eric Sosa, (Summer 2019)

Julio Flores, (Summer 2019)

Ian MacArthur, (Summer 2019)

Jessie Valencia, (Summer 2018)

PhD students:

Anastasia Nizhnik, (Block II 2019-2020)

Harmony Ketchum, (Block I 2019-2020)

Felix Liang, (Block III 2017-2018)

Blair Schneider, (Block II 2017-2018)
Helen Belalcazar, (Block III 2015-2016)

Undergraduate Interns:

Christopher Hunter, Summer 2019 (Senior, University of New Mexico, NM)

Jessica Chung, Summer 2016 (Senior, Smith College, Northampton, MA)
Benjamin Cattau, Summer 2016 (Junior, Haverford College, Haverford, PA)
Desiree Williams, Fall 2015 (Senior, John Jay College, New York City, NY)
Omer Naseer, Summer 2015 (Junior, Queens College of CUNY, Flushing, NY)

Former Fellows:

Mirunalini Ravichandran, PhD, (2017-2019)

Run Lei, PhD, (2015-2017)

Katherine Howgego, MBCHB, (2015-2016)

Collaborators

Deyou Zheng, PhD (Professor of Genetics and Neurology, Einstein)
Keisuke Ito, MD PhD (Associate Professor of Cell Biology and Medicine, Einstein)

Paul Frenette, MD (Professor of Cell Biology and Medicine, Einstein)

Cristina Montagna, PhD (Associate Professor of Genetics and Pathology, Einstein)

Amit Verma, MD (Professor of Medicine and Developmental Biology, Einstein)

Anirban Maitra, MD (Professor of Pathology, MD Anderson  Cancer Center)

Dawlaty Laboratory @ Albert Einstein College of Medicine, New York, USA