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Our publications are listed below (latest first) and can be downloaded from PubMed.

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  1. Ketchum HC, Masako S, and Dawlaty MM, Catalytic-dependent and independent roles of TET3 in the regulation of specific genetic programs during neuroectoderm specification , Communications Biology, April (2024), PMID: 38580843

  2. Flores JC, Sidoli S, and Dawlaty MM, Tet2 regulates Sin3a recruitment at active enhancers in embryonic stem cells, iScience, June (2023), PMID: 37456851

  3. Flores JC*, Ito Ky*(co-first author), Huang C, Tang Q, Yanase C, Ito K** and Dawlaty MM**, Comparative analysis of Tet2 catalytic deficient and knockout bone marrow over time, Experimental Hematology, May (2023), PMID: 37225048

  4. Chrysanthou S, Flores FC, Dawlaty MM, Tet1 Suppresses p21 to Ensure Proper Cell Cycle Progression in Embryonic Stem Cells, Cells, April (2022), PMID: 35456045

  5. Abou-Jaoude A, Huang C, Flores JC, Ravichandran M, Lei R, Chrysanthou S, and Dawlaty MM, Idax and Rinf facilitate expression of Tet enzymes to promote neural and suppress trophectodermal programs during differentiation of embryonic stem cells, Stem Cell Research, March (2022), PMID:35390758

  6. Ma L, Tang Q, Gao X, Lee J, Lei R, Suzuki M, Zheng D., Ito K, Frenette PS, and Dawlaty M.M., Tet-mediated DNA demethylation regulates specification of hematopoietic stem and progenitor cells during mammalian embryogenesis, Science Advances, March (2022), PMID:35235365

  7. Chrysanthou S*, Tang Q* (co-first authors), Lee J, Taylor SJ, Zhao Y, Steidl U, Zheng D, Dawlaty M.M, The DNA dioxygenase Tet1 regulates H3K27 modification and embryonic stem cell biology independent of its catalytic activity, Nucleic Acid Research, February (2022), PMID: 35456045

  8. Aronson BE, Scourzic L, Shah V, Swanzey E, Kloetgen A, Polyzos A, Sinha A, Azziz A, Caspi I, Li J, Pelham-Webb B, Glenn RA, Vierbuchen T, Wichterle H, Tsirigos A, Dawlaty MM, Stadtfeld M, Apostolou E. A bipartite element with allele-specific functions safeguards DNA methylation imprints at the Dlk1-Dio3 locus. Developmental Cell. November (2021) PMID: 34710357

  9. MacArthur I.C. and Dawlaty M.M., TET enzymes and 5-hydroxymethylcytosine in neural progenitor cell biology and neurodevelopment, Front. in Cell & Dev. Biology, February (2021) PMID: 33681230

  10. Bray J., Dawlaty M.M., Verma A., Maitra M., Roles and Regulations of TET enzymes in Solid Tumors, Trends in Cancer, January (2021) PMID: 33468438

  11. Bhagat T., Ahgrens D.V., Dawlaty M.M., Zou Y., Joelle Baddour J., Achreja A., Zhao H., Yang L., Patel B., Kang C., Choudhary G., Gordon-Mitchell S., Alluri S., Bhattacharyya S., Sahu S., Yu Y., Bartenstein M., Giricz O., Suzuki M., Sohal D., Gupta S., Guerrero P., Batra S., Goggins M., Steidl U., Greally J., Agarwal B., Pradhan K., Banerjee D., Nagrath D., Maitra A., and Verma A., Lactate-mediated epigenetic reprogramming regulates formation of pancreatic cancer-associated fibroblasts, eLife, November (2019), PMID: 31663852

  12. Ito Ky.*, Lee J*(co-first author), Chrysanthou S., Zhao Y., Josephs K., Sato H., Teruya-Feldstein J., Zheng D., Dawlaty M.M.**(co-corresponding author), and Ito K.**, Non-catalytic roles of Tet2 are essential to regulate hematopoietic stem and progenitor cell homeostasis, Cell Reports, vol. 28 (10), September (2019)

  13. Ravichandran M*, Lei R.*(co-first author), Tang Q., Zhao Y., Lee J., Ma L., Chrysanthou S., Lorton B., Cvekl A., Shechter D., Zheng D., and Dawlaty M.M., Rinf regulates pluripotency network genes and Tet enzymes in embryonic stem cells, Cell Reports, vol. 28 (8), pages 1993-2003, August (2019)

  14. Bhattacharyya S., Pradhan K., Campbell N., Mazdo J., Vasantkumar A., Maqbool S., Bhagat T., Gupta G., Suzuki M., Yu Y., Greally J., Steidl U., Bradner J., Dawlaty M.M., Godley L., Maitra A., Verma A. Altered Hydroxymethylation is seen at regulatory regions in pancreatic cancer and regulates oncogenic pathways, Genome Research, vol. 27, pages 1830-1842, November (2017)

  15. Feng J., Pena C., Purushothaman I., Engmann O.., Waker D., Issler O, Brown A., Doyle M., Harrigan E., Mouzon E., Vialou V., Shen L., Dawlaty M.M., Jaenisch R., Nestler E., Role of Tet1 in regulation of gene expression in nucleus accumbens, Neuropsychopharmacology, vol. 42, pages1667-1659, January (2017)

  16. Yang J., Guo R., Wang H., Ye X., Zhou Z., Dan J., Wang H, Gong P., Deng W., Yin Y., Mao S., Wang L., Ding J., Li J, Keefe D.L., Dawlaty M.M., Wang J., Xu G., Liu L., Tet Enzymes Regulate Telomere Maintenance and Chromosomal Stability of Mouse ESCs, Cell Reports, vol.15(8), pages 1809-21. May (2016)

  17. Zhao Z. *, Chen L.*, Dawlaty M.M.* (co-first author), Pan F., Li Z., Zhou Y., Cao Z., Shi H., Wang J., Lin L., Chen S., Weeks O., Yuan W., Qin Z, Ni H., Yang FC., Jaenisch R.**, Jin P**, Xu M**., Combined loss of Tet1 and Tet2 promotes B-cell, but not myeloid malignancies in mice, Cell Reports, vol.13(8), pages 1692-1704, November (2016)

  18. Wiehle L., Raddatz G., Musch T., Dawlaty M.M., Jaenisch R.J., Lyko F., and Breiling A., Tet1 and Tet2 protect DNA methylation canyons against hypermethylation, Molecular Cell Biology, vol. 36 (3), pages 452-461, November (2015)

  19. Cimmino L.*, Dawlaty M.M.* (co-first author), Ndiaye-Lobry D., Yap Y. S., Bakogianni S., Yu Y., Bhattacharyya S., Shaknovich R., Geng H., Oricchio E., Lobry C., Mullenders J., King B., Trimarchi T., Aranda-Orgilles B., Liu C., Shen S., Wendel G., Verma A.K., Jaenisch R.**, and Aifantos I. **,Tet1 is a tumor suppressor of hematopoietic malignancy, Nature Immunology, vol. 16, pages 653-652, April (2015)

  20. Theunissen T.W., Powell B.E., Wang H., Mitalipova M., Faddah D., Reddy R., Fan Z.P., Maetzel D., Ganz K., Shi L., Lungjangwa T., Imsoonthornruksa S.,Stelzer Y., Rangarajan S., D’Alessio A, Zhang J., Gao Q., Dawlaty M.M., Young R.A., Gray N.S. and Jaenisch R., Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency, Cell Stem Cell, vol. 15(4), pages 471-478, October (2014)

  21. Dawlaty M.M., Breiling A., Le T., Barrasa I.M., Raddatz G., Gao Q., Powell B.E., Cheng A.W., Faull K.F., Lyko F., and Jaenisch R., Loss of Tet enzymes compromises proper differentiation of embryonic stem cells, Developmental Cell, vol. 29(1), pages 102-111, April (2014)

  22. Rudenko A.*, Dawlaty M.M.* (co-first author), Seo J., Cheng A.W., Meng J., Le T, Faull K.F., Jaenisch R**, and Tsai L-H**,Tet1 is critical for neuronal activity-regulated gene expression and memory extinction, Neuron, vol. 79 (6), pages 1109-1122, September (2013)

  23. Huang H., Jiang X., Li Z., Li Y., Song X., He C., Sun M., Chen P., Gurbuxani S., Wang J., Hong G., Elkahloun A., Arnovitz S., Wang J., Szulwach K., Lin L., Street C., Wunderlich M., Dawlaty M.M., Neilly M., Jaenisch R., Yang F., Mulloy J., Jin P., Liu P., Rowley J., Xu M., He C., and Chen J., TET1 plays an essential oncogenic role in MLL-rearranged leukemia, PNAS, vol.110(29), pages 11994-1199, July (2013)

  24. Wang H.*, Yang H.*, Shivalila C.S.*, Dawlaty M.M., Cheng A.W., Zhang F., and Jaenisch R., One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering, Cell, vol.153(4), pages 910-918, May (2013)

  25. Piccolo F.M., Bagci H., Brown K., Landeira D., Soza‐Ried J., Feytout A., Moojman D., Hajkova P., Leitch H.G., Tada T., Kriaucionis S., Dawlaty M.M., Jaenisch R., Merkenschlager M., and Fisher A.G., Different roles for Tet1 and Tet2 proteins in reprogramming-mediated erasure of imprints induced by EG cell fusion, Molecular Cell, vol. 49(6), pages 1023-1033, March (2013)

  26. Dawlaty M.M., Breiling A., Le T., Raddatz G., Barrasa I.M., Cheng A.W.,Gao Q., Powell B.E., Le Z.,  Xu M., Faull K.F., Lyko F., and Jaenisch R., Combined deficiency of Tet1 and Tet2 causes epigenetic abnormalities but is compatible with postnatal development, Developmental Cell, vol. 24(3), pages 310-323, February (2013)

  27. Baker, D.J.*,  Dawlaty M.M.*(co-first author), Wijshake T., Jeganathan K. B., Malureanu L., van Ree J. H., Crespo-Diaz R., Reyes S., Seaburg L., Shapiro V., Behfar A., Terzic A., van de Sluis B., and van Deursen J.M., Increased expression of BubR1 protects against aneuploidy and cancer and extends healthy lifespan. Nature Cell Biology, vol. 15(1), pages 96-102, December (2012)

  28. Kim J.P., Su S.C., Wang H., Cheng A.W., Cassady J.P., Lodato M.A., Lengner C.J., Chung C-Y., Dawlaty M.M., Tsai L-H. & Jaenisch R.,  Functional integration of dopaminergic neurons directly converted from mouse fibroblasts,  Cell Stem Cell, vol. 9(5), pages 413-419, November (2011)

  29. Dawlaty M.M., Ganz K., Powell B.E., Hu Y.C., Markoulaki S., Cheng A.Q., Gao Q., Kim J., Choi S.W., Page D.C., and Jaenisch R., Tet1 is dispensable for maintaining pluripotency and its loss is compatible with embryonic and postnatal development. Cell Stem Cell, vol. 9(2), pages 166-175, August (2011)

  30. Kim J.P., Lengner C.J., Kirak O., Hanna .J, Cassady J.P., Lodato M.A., Wu S., Faddah D.A., Steine E.J., Gao Q., Fu D., Dawlaty M.M. & Jaenisch R.,  Reprogramming of postnatal neurons into induced pluripotent stem cells by defined factors.  Stem Cells, vol. 29(6), pages 992-1000, June (2011)

  31. Staerk J., Dawlaty M.M., Gao Q., Maetzel D., Hanna J., Sommer C.A., Mostoslavsky G., & Jaenisch, R.  Reprogramming of human peripheral blood cells to induced pluripotent stem cells. Cell Stem Cell, vol.7(1), pages 20-24, July (2010)

  32. Dawlaty M. M., Malureanu L., Jeganathan K. B., Kao E., Sustmann C., Tahk S.,  Shuai K., Grosschedl R., and van Deursen, J. M., Resolution of sister centromeres requires RanBP2-mediated SUMOylation of Topoisomerase IIa. Cell, vol. 133 (1), pages 103-115,  April (2008)

  33. Baker D.J., Dawlaty M.M., Galardy P., and van Deursen J.M., Mitotic regulation of the anaphase promoting complex (APC/C), Cell & Molecular Life Sciences, vol. 64(5), pages 589-600, March (2007)

  34. Dawlaty M.M., and van Deursen J.M., Gene targeting methods for studying nuclear transport factors in mice. Methods, vol. 39(4), 370-378, August (2006)

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